Endocrine Disruptors

 In vitro Evaluation of Endocrine Disruptors, level 2 OECD 2002

Target fields : Primary packaging, Cosmetics, Medical devices, Chemicals, Food industry, Pesticides or new substances, Nano-substances, Processed waste, Pollutants and Micro-pollutants….


OECD Assays:

An In vitro biological test of level 2 OECD 2002 (Conceptual frame)

  • Detection of oestrogen receptors agonists/antagonists (OECD 455)

Performance-based test guideline for stably transfected transactivation In vitro assays to detect oestrogen receptors agonists/antagonists (OECD 455)

  • H295R steroidogenesis assay (OECD 456)


Other available tests (partnership)

  • Androgen receptor agonists/antagonists (OECD 458)

  • Triiodothyronine (TR), Obesogens (PPAR), Dioxins/PCBs (AhR)

    endocrine disruptors

Agonist response to oestrogen

schéma endocrine disruptors